Two new antifungal metabolites produced by Sparassis crispa in culture and in decayed trees


WOODWARD S., Sultan H., Barrett D., Pearce R.

Journal of General Microbiology, cilt.139, sa.1, ss.153-159, 1993 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 139 Sayı: 1
  • Basım Tarihi: 1993
  • Doi Numarası: 10.1099/00221287-139-1-153
  • Dergi Adı: Journal of General Microbiology
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.153-159
  • Isparta Uygulamalı Bilimler Üniversitesi Adresli: Evet

Özet

The basidiomycete fungus Sparassis crispa produced three antifungal compounds during submerged culture in 2% malt broth. One compound appeared to be sparassol (methyl-2-hydroxy-4-methoxy-6-methylbenzoate), first characterized in 1924. The other two, termed ScI and ScII, exhibited considerably greater antifungal activity than did sparassol against Cladosporium cucumerinum, and were characterized as methyl-2,4-dihydroxy-6-methylbenzoate (methyl orsellinate) and an incompletely determined methyl-dihydroxy-methoxy-methylbenzoate, respectively. Both compounds were found in the decayed wood of trees, where their presence was diagnostic of S. crispa infection. The possible ecological role of these compounds is discussed.