Fig seed oil-loaded nanostructured lipid carriers: Evaluation of the protective effects against oxidation


ERDOĞAN Ü., Gökçe E. H.

Journal of Food Processing and Preservation, cilt.45, sa.10, 2021 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 10
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1111/jfpp.15835
  • Dergi Adı: Journal of Food Processing and Preservation
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), Biotechnology Research Abstracts, Business Source Elite, Business Source Premier, CAB Abstracts, Compendex, Food Science & Technology Abstracts, INSPEC, Veterinary Science Database
  • Isparta Uygulamalı Bilimler Üniversitesi Adresli: Evet

Özet

The aim of this study was to develop a carrier system that protects fig seed oil (FSO) from oxidation by encapsulating into nanostructured lipid carriers (NLCs). NLCs were prepared by high shear mixing technique and the effects of solid lipids and surfactants on the formulation parameters were investigated. The formulations were characterized in terms of particle size, polydispersity index, and zeta potential, and fatty acid and tocopherol amounts were determined by GC and HPLC, respectively. NLC loaded with FSO was obtained at a particle size of 241 nm with low polydispersity (0.259) and a negative electrical charge (−13.6 mV). The antioxidant capacity has been evaluated by accelerated oxidation storage tests, radical and hydrogen peroxide scavenging activity tests. The stability of the final formulation with high concentration of gamma tocopherol and unsaturated linoleic acid content of FSO was increased by loading into NLCs. Novelty impact statement: NLC formulations loaded with FSO were prepared for the first time at a dimension of 241 nm with low polydispersity. FSO was protected against lipid oxidation by encapsulation into NLC as revealed by lipid peroxidation, hydrogen peroxide, and radical scavenging activity tests. FSO-loaded NLC formulations were shown to be valuable carriers for encapsulation of bioactive food materials for stability.