Interleukin-6 levels in hyperemesis gravidarum
Archives of Gynecology and Obstetrics, vol.269, no.1, pp.13-15, 2003 (Scopus)
- Publication Type: Article / Article
- Volume: 269 Issue: 1
- Publication Date: 2003
- Doi Number: 10.1007/s00404-002-0412-6
- Journal Name: Archives of Gynecology and Obstetrics
- Journal Indexes: Scopus
- Page Numbers: pp.13-15
- Keywords: Hyperemesis, IL-6, Pregnancy, Thyroid
- Isparta University of Applied Sciences Affiliated: No
Abstract
Introduction: Hyperemesis gravidarum (HG) is associated with higher levels of serum β-hCG levels and hyperthyroidism. Interleukin-6 (IL-6), a pro-inflammatory cytokine, is reported to enhance secretion of β-hCG from trophoblastic cell line. Methods: We measured serum levels of IL-6, thyroid hormones and β-hCG of hyperemetic patients and gestational age-matched controls to search for a difference between the two groups. Results: There was a significant difference in β-hCG (p=0.028), though IL-6 levels were higher in the hyperemetic group, it did not reach a significant level. Interleukin-6 positively correlated with β-hCG (r=0.38 and p=0.13).