Development of a Novel Molecularly Imprinted Overoxidized Polypyrrole Electrode for the Determination of Sulfasalazine

SARDOHAN KÖSEOĞLU T., Durgut A.

Electroanalysis, cilt.32, sa.9, ss.2072-2081, 2020 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 9
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1002/elan.202060036
  • Dergi Adı: Electroanalysis
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Applied Science & Technology Source, BIOSIS, Chimica, Communication Abstracts, Metadex, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.2072-2081
  • Anahtar Kelimeler: Electrochemical Sensor, Molecularly Imprinted Polymer (MIP), Pencil Graphite Electrode (PGE), Sulfasalazine, Voltammetry.
  • Isparta Uygulamalı Bilimler Üniversitesi Adresli: Evet

Özet

A novel molecularly imprinted overoxidized polypyrrole electrode was produced for the determination of sulfasalazine (SSZ). The electrode was attained by electropolymerization of pyrrole onto a pencil graphite electrode by cyclic voltammetry. The SSZ was penetrated into the structure during the process. Differential pulse voltammetry was used to determine performance of imprinted (MIP) and non-imprinted (NIP) electrodes. The linear range was attained in the range between 1.0 to 10.0 ppm of SSZ (R2=0.9993) with a detection limit of 0.265 ppm. The developed MIP electrode and analysis method are suitable for analysis of SSZ with reproducible response and precision in real samples.